Single IRB of Record Information

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IRBMED and Central IRBs: Frequently Asked Questions

Performance Site Listing Spreadsheet

MULTI-SITE RESEARCH

For information about single institutional review board (or sIRB) for multisite research, view our U-MIC titled "Single Institutional Review Board for Multisite Research (NIH Policy)."

U-M as a Coordinating Center

  • A coordinating center is an institution, department or center that agrees to be responsible for the conduct and administrative or coordinating functions of a multicenter research project.

U-M as IRB of Record

  • An IRB of record is a reviewing IRB that assumes IRB responsibilities for another institution and is designated to do so through an approved federalwide assurance on file with the federal Office for Human Research Protections.

WORKING WITH CENTRAL IRBs

U-M has finalized Master Services Agreements with several IRBs:

  • Advarra
  • NCI CIRB (CIRB)
  • Quorum Review IRB
  • Western IRB (WIRB)

Under these Agreements, U-M may cede regulatory oversight of new, industry-sponsored, Phase 3 or 4 multi-site trials to one of these central IRBs. 

Study teams will need to complete the "Request Review by a Non-UM IRB" (AKA, Ceding) Application within eResearch and receive an acknowledgement letter in addition to completing the electronic site application for the central IRB of choice. Study teams must receive the U-M acknowledgement letter and the central IRB approval notice before beginning any research related activities.

For more information about working with one of the listed IRBs, click on the links below:

Advarra (formerly Chesapeake IRB and Schulman IRB)

NCI CIRB (CIRB)

Quorum Review IRB

Western IRB (WIRB)

Non-UM Academic or Other Consortiums

 

Questions?

Contact us at irbmed@umich.edu or 734-763-4768 / (Fax 734-763-1234)
2800 Plymouth Road, Building 520, Room 3214, Ann Arbor, MI 48109-2800

A list of IRBMED staff is available in the Personnel Directory, or view the list of Regulatory Teams.