Central Biorepository Spotlight: Bipolar Disorder

The Heinz C. Prechter Bipolar Research Program's Longitudinal Study of Bipolar Disorder

The Prechter Program’s Longitudinal Study of Bipolar Disorder is an active study of the Central Biorepository (CBR), a unit of the UMMS Office of Research, which facilitates discovery and improves healthcare outcomes by providing high-quality, highly annotated biospecimens donated for basic, clinical and translational research.

The unit receives biospecimens and data from U-M contributors and collaborators across a spectrum of medical research. These samples, annotated with clinical and research data, are accessible to members of the U-M research enterprise.

Types of Biospecimens

• DNA
• Plasma

Population

1,200 participants, with more than 700+ of those individuals having samples in the Central Biorepository. The study is currently enrolling participants with:

• Bipolar disorder
• No first-degree family history of mental health disorder

Access

The Central Biorepository enables access to thousands of Prechter biospecimens from Michigan Medicine patients and offers secure linkage to laboratory and clinical data offered by the Data Office.

Get started:

• Search the Bipolar Disease cohort on the self-serve tool, DataDirect.
• Complete and submit a CBR Use Proposal Form available on research.medicine.umich.edu/biorepository and send to CBR.requests@umich.edu.
• With IRB and oversight committee approval, datasets can be downloaded

"Our flagship Longitudinal Study of Bipolar Disorder reflects the participation and contributions of countless individuals. Through the experiences volunteered by so many, we will gain greater knowledge and understanding to form the base for improved treatments for this illness."- Melvin McInnis, M.D., Professor

The Heinz C. Prechter Bipolar Research Program

The Prechter Program’s Longitudinal Study of Bipolar Disorder aims to discover the underlying biological mechanisms of bipolar illness. Through cellular and genetic research, new technologies and clinical assessments, Prechter researchers establish the biological mechanisms and patterns of personal behavior that will enable them to identify disease course, predict mood changes, and intervene early and effectively.

Learn more

View the full study sheet