Epigenomics Core

Getting Started with the Epigenomics Core

The Epigenomics Core uses MiCores, an online core management system, to process Core requests and billing. All new and existing users are invited to use the system, which you can access using your Uniqname and level-1/Kerberos password if you are affiliated with U-M. Once you complete the one-time registration process and are approved by your PI or Lab Manager, the system will enable you to place service requests, provide required approvals, and monitor progress.

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To set up a new account or login, visit: https://umich.corefacilities.org.

If you have any questions, please contact msishelp@umich.edu or visit the MiCores Help Wiki.

"An Introduction to Epigenetic Regulation: What Each of the Services Can do for Your Research"

In June 2015, Founding Faculty Director Maria Figueroa, M.D., presented an introduction to epigenetics at the 2015 BRCF Technoloy & Services Showcase. Download a copy of her slides here. Thanks to everyone who joined us for the event. If you have other topics you'd like to see discussed at future BRCF events, please contact us.

About the Core

The Epigenomics Core, launched in 2015 as part of the UMMS Office of Research and Medical School's Strategic Research Initiative, provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners. The Epigenomics Core is the newest member of the Biomedical Research Core Facilities.

 

What is Epigenetics?

Epigenetic regulation refers to DNA sequence independent regulation of heritable traits that impacts gene expression. In recent years the term has broadened to also encompass processes that control gene expression and genomic functions beyond DNA sequence but which may be more transient or facultative in nature. Epigenetic information is contained and mediated by the genomic distribution of cytosine modifications such as methylation (5mC) and hydroxymethylation (5hmC), and post-translational modifications of histones and other proteins.

To learn more about the Epigenomics Core, download the flyer.

Consultation requests are by email only. Please contact the Managing Director with any questions or consultation requests.

Claudia Lalancette, Ph.D.

Managing Director, Epigenomics Core