The Central Biorepository (CBR) receives and distributes biospecimens and data from University of Michigan contributors across the spectrum of medical research. This includes the recently added programs, U-M Gynecology Oncology Biorepository and Personalized Medicine through Integration of Immune Phenotypes in Autoimmune Skin Disease.
The Gynecology Oncology Biorepository is a study with the overall goal of improving the prevention, diagnosis and treatment of gynecologic oncology. Biological samples will be obtained from human Gynecologic Oncology patients and there will be a mechanism to link these specimens to health information for research projects within the departments of Obstetrics and Gynecology, as well as colleagues from other units.
The new Personalized Medicine through Integration of Immune Phenotypes in Autoimmune Skin Disease study aims to better understand autoimmune diseases, psoriasis and systemic lupus erythematosus (SLE). Samples will be carefully clinically phenotyped and coupled with longitudinal and targeted sample collection for mechanistic studies. Using existing pipelines for integration of genomic and transcriptomic data, the study will identify predictors of treatment response and disease progression, which will help revolutionize approaches to treating patients with psoriasis and SLE.