Invest in state-of-the-art, customer-centric core services
- Established the Epigenomics Core, providing resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners.
- Developed the Michigan Research Cores website.
- Across the 12 cores, we introduced new technologies, increased scientific capability and capacity, and reduced turnaround times. Collectively, the BRCF represent:
- $19M invested in new technology
- 4,650+ grants served in FY18
- 2,537 PIs served in FY18
- Established an enterprise-wide, College of American Pathologists-accredited biorepository of biospecimens linked to highly annotated clinical and laboratory data.
- Developed standard informed consent for biobanking, and foundational standard language for sharing with industry.
- Enabling Precision Health and Michigan Genomics Initiative, as well as 20+ other programs.
- Established archive biorepository for long-term storage of critical biospecimens.
- Currently offering access to nearly 500,000 specimens from 100,000 individuals.
Improve research IT
Data Office for Clinical and Translational Research & Research Data Warehouse
- In partnership, these two units were established to accelerate research by enabling secure access to patient data through investigator-friendly, self-serve tools and custom data extracts.
- Developed DataDirect, a web-based self-serve tool that enables access to clinical data including diagnoses, encounters, procedures, medications, and labs on over four million unique patients from across Michigan Medicine.
- Currently 2,000+ active users of DataDirect, and almost 1,000 data extracts are delivered to U-M researchers annually.
- The Data Office and Research Data Warehouse also currently enable the Precision Health Initiative, the Patient-Centered Outcomes Research Institute, the Pediatric Trial Network, and the Clinical Trials Recruitment Roadmap.
Accelerate innovation and commercialization
- Established to support a campus-wide biomedical entrepreneurial ecosystem through funding channels, industry engagement, and commercialization education.
- To date, $10M in funding from the State of Michigan, 30+ startup companies, and over $50M in follow-on funding.
- $100M+ in industry sponsored awards annually, plus averaging 100+ license agreements with industry each year.
- 275 projects teams participated in commercialization education.
- In partnership with the COE Center for Entrepreneurship, launched the Michigan Biomedical Venture Fund, which channels investments into U-M biomedical startups.
Support early-career faculty in funding pursuit
- Established multifaceted program designed to help faculty members receive their first R01 grants from the NIH.
- Senior faculty with strong track records of NIH funding guide groups of mentees through the proposal development process.
- Team structure encourages peer support and feedback.
- 175+ participants, and over 50 new R01s (or equivalent) to date.
Transform the clinical trials enterprise
- Established central hub for seven trans-departmental Clinical Trial Support Units (CTSU) providing enterprise-wide leadership, standards, policies, and common infrastructure for all clinical trials at the U-M. The Clinical Trials Support Units include:
- Accute, Critical Care, Surgery, and Transplant CTSU
- Ambulatory and Chronic Disease CTSU
- Behavior, Function, and Pain CTSU
- Children's CTSU
- Heart, Vessel, Blood CTSU
- Neurosciences and Sensory CTSU
- Oncology CTSU
- Launched OnCore clinical trials management system.
- Redesigned IRBMED to expedite regulatory review.
- 1,800+ active clinical trials FY19.
Support research strengths
- Launched collaborative initiative built upon long-standing strengths in microbiology, microbial pathogenesis, immunology, and clinical medicine.
- $11M initial funding, with $64M achieved in follow-on external funding.
- 139 investigators across campus.
- Microbial Systems Molecular Biology Laboratory launched to serve the entire U-M biomedical research community.
- Four research “hubs” under the umbrella of one initiative focusing on disorders of abnormal protein accumulations and perturbations in protein quality control.
- $30M in external funding.
- 60+ investigators.
- Hosts annual symposium.
- First center of its kind in the country.